Geniposide Protects against Obesity-Related Cardiac Injury through AMPKα- and Sirt1-Dependent Mechanisms

Our previous study found that geniposide, an agonist of glucagon-like peptide-1 receptor (GLP-1R), protected against cardiac hypertrophy via the activation of AMP-activated protein kinase α (AMPKα). However, the effects of geniposide on obesity-related cardiac injury remain unknown. Here, we examine...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oxid Med Cell Longev
Main Authors: Ma, Zhen-Guo, Kong, Chun-Yan, Song, Peng, Zhang, Xin, Yuan, Yu-Pei, Tang, Qi-Zhu
Format: Artigo
Jezik:Inglês
Izdano: Hindawi 2018
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6247476/
https://ncbi.nlm.nih.gov/pubmed/30533173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/6053727
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