Osteocrin attenuates inflammation, oxidative stress, apoptosis, and cardiac dysfunction in doxorubicin‐induced cardiotoxicity

BACKGROUND: Inflammation, oxidative stress, and apoptosis contribute to the evolution of doxorubicin (DOX)‐induced cardiotoxicity. Osteocrin (OSTN) is a novel secretory peptide mainly derived from the bone and skeletal muscle, and plays critical roles in regulating bone growth and physical endurance...

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Udgivet i:Clin Transl Med
Main Authors: Hu, Can, Zhang, Xin, Zhang, Ning, Wei, Wen‐Ying, Li, Ling‐Li, Ma, Zhen‐Guo, Tang, Qi‐Zhu
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7418805/
https://ncbi.nlm.nih.gov/pubmed/32618439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ctm2.124
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