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Levosimendan Protects against Doxorubicin-Induced Cardiotoxicity by Regulating the PTEN/Akt Pathway
BACKGROUND AND AIMS: Myocyte apoptosis plays a critical role in the development of doxorubicin- (DOX-) induced cardiotoxicity. In addition to its cardiotonic effect, laboratory evidence indicates that levosimendan can inhibit apoptosis, but its role in DOX-induced cardiac injury remains unclear. The...
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| Published in: | Biomed Res Int |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Hindawi
2020
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7298255/ https://ncbi.nlm.nih.gov/pubmed/32596387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/8593617 |
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