VEGFR inhibitors upregulate CXCR4 in VEGF receptor-expressing glioblastoma in a TGFβR signaling-dependent manner

The failure of standard treatment for patients diagnosed with glioblastoma (GBM) coupled with the highly vascularized nature of this solid tumor has led to the consideration of agents targeting VEGF or VEGFRs, as alternative therapeutic strategies for this disease. Despite modest achievements in sur...

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Bibliografiska uppgifter
I publikationen:Cancer Lett
Huvudupphovsmän: Pham, Kien, Luo, Defang, Siemann, Dietmar W., Law, Brian K., Reynolds, Brent A., Hothi, Parvinder, Foltz, Gregory, Harrison, Jeffrey K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7294457/
https://ncbi.nlm.nih.gov/pubmed/25676691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2015.02.005
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