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AI-24 VEGFR INHIBITORS ENHANCE PROGRESSION OF GLIOBLASTOMA BY UPREGULATING CXCR4 IN A TGFβR SIGNALING-DEPENDENT MANNER

The failure of standard of care treatment for patients diagnosed with glioblastoma (GBM) coupled with the highly vascularized nature of this solid tumor has led to the consideration of agents that target vascular endothelial growth factor (VEGF) or its receptors, as alternative therapeutic strategie...

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Detalhes bibliográficos
Main Authors: Pham, Kien, Luo, Defang, Siemann, Dietmar, Law, Brian, Reynolds, Brent, Hothi, Parvinder, Foltz, Gregory, Harrison, Jeffrey
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217863/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou238.24
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