CBIO-11. UPREGULATION OF THE TGF-β PATHWAY DRIVES TRANSFORMATION OF GLIOBLASTOMA INTO GLIOSARCOMA AND OSTEOSARCOMA

INTRODUCTION: Gliosarcoma, a histopathological variant of glioblastoma, is defined by clonal biphasic differentiation into gliomatous and sarcomatous components. The underlying molecular mechanisms driving the transformation of glioblastoma to gliosarcoma are unclear. We observed a patient with glio...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Li, Aiguo, Ranjan, Surabhi, Ahn, Susie, Celiku, Orieta, Kim, Sun A, Quezado, Martha, Nduom, Edjah, Gilbert, Mark R, Park, Deric M
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692812/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.133
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