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Computational modeling demonstrates that glioblastoma cells can survive spatial environmental challenges through exploratory adaptation

Glioblastoma (GBM) is an aggressive type of brain cancer with remarkable cell migration and adaptation capabilities. Exploratory adaptation—utilization of random changes in gene regulation for adaptive benefits—was recently proposed as the process enabling organisms to survive unforeseen conditions....

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Dades bibliogràfiques
Publicat a:Nat Commun
Autors principals: Celiku, Orieta, Gilbert, Mark R., Lavi, Orit
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6911112/
https://ncbi.nlm.nih.gov/pubmed/31836713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13726-w
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