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Computational modeling demonstrates that glioblastoma cells can survive spatial environmental challenges through exploratory adaptation

Glioblastoma (GBM) is an aggressive type of brain cancer with remarkable cell migration and adaptation capabilities. Exploratory adaptation—utilization of random changes in gene regulation for adaptive benefits—was recently proposed as the process enabling organisms to survive unforeseen conditions....

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Bibliographic Details
Published in:Nat Commun
Main Authors: Celiku, Orieta, Gilbert, Mark R., Lavi, Orit
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6911112/
https://ncbi.nlm.nih.gov/pubmed/31836713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13726-w
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