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Computational modeling demonstrates that glioblastoma cells can survive spatial environmental challenges through exploratory adaptation

Glioblastoma (GBM) is an aggressive type of brain cancer with remarkable cell migration and adaptation capabilities. Exploratory adaptation—utilization of random changes in gene regulation for adaptive benefits—was recently proposed as the process enabling organisms to survive unforeseen conditions....

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Detalles Bibliográficos
Publicado en:Nat Commun
Main Authors: Celiku, Orieta, Gilbert, Mark R., Lavi, Orit
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6911112/
https://ncbi.nlm.nih.gov/pubmed/31836713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13726-w
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