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VEGF-C-VEGFR3/Flt4 axis regulates mammary tumor growth and metastasis in an autocrine manner

Purpose: Lymphangiogenic factors, such as vascular endothelial growth factor-C (VEGF-C) and VEGFC-D, and their receptor, VEGF receptor-3 (VEGFR3), play a pivotal role in the promotion of metastasis to regional lymph nodes. In the present study we explored the role of VEGF-C as an autocrine growth fa...

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Pubblicato in:Am J Cancer Res
Autori principali: Varney, Michelle L, Singh, Rakesh K
Natura: Artigo
Lingua:Inglês
Pubblicazione: e-Century Publishing Corporation 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396036/
https://ncbi.nlm.nih.gov/pubmed/25973301
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