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Human Purkinje in silico model enables mechanistic investigations into automaticity and pro-arrhythmic abnormalities

Cardiac Purkinje cells (PCs) are implicated in lethal arrhythmias caused by cardiac diseases, mutations, and drug action. However, the pro-arrhythmic mechanisms in PCs are not entirely understood, particularly in humans, as most investigations are conducted in animals. The aims of this study are to...

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Bibliographische Detailangaben
Veröffentlicht in:J Mol Cell Cardiol
Hauptverfasser: Trovato, Cristian, Passini, Elisa, Nagy, Norbert, Varró, András, Abi-Gerges, Najah, Severi, Stefano, Rodriguez, Blanca
Format: Artigo
Sprache:Inglês
Veröffentlicht: Academic Press 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7294239/
https://ncbi.nlm.nih.gov/pubmed/32251669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2020.04.001
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