Mechanisms of pro-arrhythmic abnormalities in ventricular repolarisation and anti-arrhythmic therapies in human hypertrophic cardiomyopathy

INTRODUCTION: Hypertrophic cardiomyopathy (HCM) is a cause of sudden arrhythmic death, but the understanding of its pro-arrhythmic mechanisms and an effective pharmacological treatment are lacking. HCM electrophysiological remodelling includes both increased inward and reduced outward currents, but...

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Detalles Bibliográficos
Publicado en:J Mol Cell Cardiol
Main Authors: Passini, Elisa, Mincholé, Ana, Coppini, Raffaele, Cerbai, Elisabetta, Rodriguez, Blanca, Severi, Stefano, Bueno-Orovio, Alfonso
Formato: Artigo
Idioma:Inglês
Publicado: Academic Press 2016
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4915817/
https://ncbi.nlm.nih.gov/pubmed/26385634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2015.09.003
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