טוען...

Drug‐induced shortening of the electromechanical window is an effective biomarker for in silico prediction of clinical risk of arrhythmias

BACKGROUND AND PURPOSE: Early identification of drug‐induced cardiac adverse events is key in drug development. Human‐based computer models are emerging as an effective approach, complementary to in vitro and animal models. Drug‐induced shortening of the electromechanical window has been associated...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Br J Pharmacol
Main Authors: Passini, Elisa, Trovato, Cristian, Morissette, Pierre, Sannajust, Frederick, Bueno‐Orovio, Alfonso, Rodriguez, Blanca
פורמט: Artigo
שפה:Inglês
יצא לאור: John Wiley and Sons Inc. 2019
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6780030/
https://ncbi.nlm.nih.gov/pubmed/31271649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14786
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