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The Cardiac Pacemaker Story—Fundamental Role of the Na(+)/Ca(2+) Exchanger in Spontaneous Automaticity

The electrophysiological mechanism of the sinus node automaticity was previously considered exclusively regulated by the so-called “funny current”. However, parallel investigations increasingly emphasized the importance of the Ca(2+)-homeostasis and Na(+)/Ca(2+) exchanger (NCX). Recently, increasing...

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Pubblicato in:Front Pharmacol
Autori principali: Kohajda, Zsófia, Loewe, Axel, Tóth, Noémi, Varró, András, Nagy, Norbert
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7199655/
https://ncbi.nlm.nih.gov/pubmed/32410993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00516
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