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(19)F NMR reveals the conformational properties of free thrombin and its zymogen precursor prethrombin-2
The conformational properties of trypsin-like proteases and their zymogen forms remain controversial because of a lack of sufficient information on their free forms. Specifically, it is unclear whether the free protease is zymogen-like and shifts to its mature form upon a ligand-induced fit or exist...
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| Publicado no: | J Biol Chem |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7294081/ https://ncbi.nlm.nih.gov/pubmed/32358061 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013419 |
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