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Crystal structure of prethrombin-1

Prothrombin is the zymogen precursor of the clotting enzyme thrombin, which is generated by two sequential cleavages at R271 and R320 by the prothrombinase complex. The structure of prothrombin is currently unknown. Prethrombin-1 differs from prothrombin for the absence of 155 residues in the N-term...

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Detalhes bibliográficos
Main Authors: Chen, Zhiwei, Pelc, Leslie A., Di Cera, Enrico
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2984181/
https://ncbi.nlm.nih.gov/pubmed/20974933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1010262107
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