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Crystal structure of prethrombin-1

Prothrombin is the zymogen precursor of the clotting enzyme thrombin, which is generated by two sequential cleavages at R271 and R320 by the prothrombinase complex. The structure of prothrombin is currently unknown. Prethrombin-1 differs from prothrombin for the absence of 155 residues in the N-term...

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Autors principals: Chen, Zhiwei, Pelc, Leslie A., Di Cera, Enrico
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2984181/
https://ncbi.nlm.nih.gov/pubmed/20974933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1010262107
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