A kinase-deficient NTRK2 splice variant predominates in glioma and amplifies several oncogenic signaling pathways

Independent scientific achievements have led to the discovery of aberrant splicing patterns in oncogenesis, while more recent advances have uncovered novel gene fusions involving neurotrophic tyrosine receptor kinases (NTRKs) in gliomas. The exploration of NTRK splice variants in normal and neoplast...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Nat Commun
Autors principals: Pattwell, Siobhan S., Arora, Sonali, Cimino, Patrick J., Ozawa, Tatsuya, Szulzewsky, Frank, Hoellerbauer, Pia, Bonifert, Tobias, Hoffstrom, Benjamin G., Boiani, Norman E., Bolouri, Hamid, Correnti, Colin E., Oldrini, Barbara, Silber, John R., Squatrito, Massimo, Paddison, Patrick J., Holland, Eric C.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7293284/
https://ncbi.nlm.nih.gov/pubmed/32532995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16786-5
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars