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Variability in estimated gene expression among commonly used RNA-seq pipelines

RNA-sequencing data is widely used to identify disease biomarkers and therapeutic targets using numerical methods such as clustering, classification, regression, and differential expression analysis. Such approaches rely on the assumption that mRNA abundance estimates from RNA-seq are reliable estim...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Arora, Sonali, Pattwell, Siobhan S., Holland, Eric C., Bolouri, Hamid
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7026138/
https://ncbi.nlm.nih.gov/pubmed/32066774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-59516-z
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