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DXO/Rai1 enzymes remove 5′-end FAD and dephospho-CoA caps on RNAs

In eukaryotes, the DXO/Rai1 enzymes can eliminate most of the incomplete and non-canonical NAD caps through their decapping, deNADding and pyrophosphohydrolase activities. Here, we report that these enzymes can also remove FAD and dephospho-CoA (dpCoA) non-canonical caps from RNA, and we have named...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Doamekpor, Selom K, Grudzien-Nogalska, Ewa, Mlynarska-Cieslak, Agnieszka, Kowalska, Joanna, Kiledjian, Megerditch, Tong, Liang
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7293010/
https://ncbi.nlm.nih.gov/pubmed/32374864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa297
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