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A novel 5′-hydroxyl dinucleotide hydrolase activity for the DXO/Rai1 family of enzymes
Modifications at the 5′-end of RNAs play a pivotal role in determining their fate. In eukaryotes, the DXO/Rai1 family of enzymes removes numerous 5′-end RNA modifications, thereby regulating RNA turnover. Mouse DXO catalyzes the elimination of incomplete 5′-end caps (including pyrophosphate) and the...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6943137/ https://ncbi.nlm.nih.gov/pubmed/31777937 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz1107 |
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