Synthesis of adenine dinucleosides SAM analogs as specific inhibitors of SARS-CoV nsp14 RNA cap guanine-N7-methyltransferase

The spreading of new viruses is known to provoke global human health threat. The current COVID-19 pandemic caused by the recently emerged coronavirus SARS-CoV-2 is one significant and unfortunate example of what the world will have to face in the future with emerging viruses in absence of appropriat...

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Bibliographische Detailangaben
Veröffentlicht in:Eur J Med Chem
Hauptverfasser: Ahmed-Belkacem, Rostom, Sutto-Ortiz, Priscila, Guiraud, Mathis, Canard, Bruno, Vasseur, Jean-Jacques, Decroly, Etienne, Debart, Françoise
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier Masson SAS. 2020
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7291971/
https://ncbi.nlm.nih.gov/pubmed/32563813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2020.112557
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