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Crystal Structure and Functional Analysis of the SARS-Coronavirus RNA Cap 2′-O-Methyltransferase nsp10/nsp16 Complex

Cellular and viral S-adenosylmethionine-dependent methyltransferases are involved in many regulated processes such as metabolism, detoxification, signal transduction, chromatin remodeling, nucleic acid processing, and mRNA capping. The Severe Acute Respiratory Syndrome coronavirus nsp16 protein is a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Decroly, Etienne, Debarnot, Claire, Ferron, François, Bouvet, Mickael, Coutard, Bruno, Imbert, Isabelle, Gluais, Laure, Papageorgiou, Nicolas, Sharff, Andrew, Bricogne, Gérard, Ortiz-Lombardia, Miguel, Lescar, Julien, Canard, Bruno
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102710/
https://ncbi.nlm.nih.gov/pubmed/21637813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002059
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