Crystal Structure and Functional Analysis of the SARS-Coronavirus RNA Cap 2′-O-Methyltransferase nsp10/nsp16 Complex

Cellular and viral S-adenosylmethionine-dependent methyltransferases are involved in many regulated processes such as metabolism, detoxification, signal transduction, chromatin remodeling, nucleic acid processing, and mRNA capping. The Severe Acute Respiratory Syndrome coronavirus nsp16 protein is a...

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Bibliographic Details
Main Authors: Decroly, Etienne, Debarnot, Claire, Ferron, François, Bouvet, Mickael, Coutard, Bruno, Imbert, Isabelle, Gluais, Laure, Papageorgiou, Nicolas, Sharff, Andrew, Bricogne, Gérard, Ortiz-Lombardia, Miguel, Lescar, Julien, Canard, Bruno
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102710/
https://ncbi.nlm.nih.gov/pubmed/21637813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002059
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