Paradoxical mitotic exit induced by a small molecule inhibitor of APC/C(Cdc20)

The Anaphase Promoting Complex/Cyclosome (APC/C) is a ubiquitin ligase that initiates anaphase and mitotic exit. The APC/C is activated by Cdc20 and inhibited by the mitotic checkpoint complex (MCC), which delays mitotic exit when the spindle assembly checkpoint (SAC) is activated. We previously ide...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Nat Chem Biol
Main Authors: Richeson, Katherine V., Bodrug, Tatyana, Sackton, Katharine L., Yamaguchi, Masaya, Paulo, Joao A., Gygi, Steven P., Schulman, Brenda A., Brown, Nicholas G., King, Randall W.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7289404/
https://ncbi.nlm.nih.gov/pubmed/32152539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-020-0495-z
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker