Defining ‘T cell exhaustion’

‘T cell exhaustion’ is a broad term that has been used to describe the response of T cells to chronic antigen stimulation, first in the setting of chronic viral infection but more recently in response to tumours. Understanding the features of and pathways to exhaustion has crucial implications for t...

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發表在:Nat Rev Immunol
Main Authors: Blank, Christian U., Haining, W. Nicholas, Held, Werner, Hogan, Patrick G., Kallies, Axel, Lugli, Enrico, Lynn, Rachel C., Philip, Mary, Rao, Anjana, Restifo, Nicholas P., Schietinger, Andrea, Schumacher, Ton N., Schwartzberg, Pamela L., Sharpe, Arlene H., Speiser, Daniel E., Wherry, E. John, Youngblood, Benjamin A., Zehn, Dietmar
格式: Artigo
語言:Inglês
出版: 2019
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7286441/
https://ncbi.nlm.nih.gov/pubmed/31570879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41577-019-0221-9
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