Defining ‘T cell exhaustion’

‘T cell exhaustion’ is a broad term that has been used to describe the response of T cells to chronic antigen stimulation, first in the setting of chronic viral infection but more recently in response to tumours. Understanding the features of and pathways to exhaustion has crucial implications for t...

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Bibliografski detalji
Izdano u:Nat Rev Immunol
Glavni autori: Blank, Christian U., Haining, W. Nicholas, Held, Werner, Hogan, Patrick G., Kallies, Axel, Lugli, Enrico, Lynn, Rachel C., Philip, Mary, Rao, Anjana, Restifo, Nicholas P., Schietinger, Andrea, Schumacher, Ton N., Schwartzberg, Pamela L., Sharpe, Arlene H., Speiser, Daniel E., Wherry, E. John, Youngblood, Benjamin A., Zehn, Dietmar
Format: Artigo
Jezik:Inglês
Izdano: 2019
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7286441/
https://ncbi.nlm.nih.gov/pubmed/31570879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41577-019-0221-9
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