The Tripartite Interaction of Phosphate, Autophagy and αKlotho in Health Maintenance

Aging-related organ degeneration is driven by multiple factors including the cell maintenance mechanisms of autophagy, the cytoprotective protein αKlotho, and the lesser known effects of excess phosphate (Pi), or phosphotoxicity. To examine the interplay between Pi, autophagy, and αKlotho, we used t...

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Опубликовано в: :FASEB J
Главные авторы: Shi, Mingjun, Maique, Jenny, Shaffer, Joy, Davidson, Taylor, Sebti, Salwa, Fernández, Álvaro F., Zou, Zhongju, Yan, Shirley, Levine, Beth, Moe, Orson W., Hu, Ming Chang
Формат: Artigo
Язык:Inglês
Опубликовано: 2020
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7286356/
https://ncbi.nlm.nih.gov/pubmed/31908069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201902127R
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