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The Tripartite Interaction of Phosphate, Autophagy and αKlotho in Health Maintenance

Aging-related organ degeneration is driven by multiple factors including the cell maintenance mechanisms of autophagy, the cytoprotective protein αKlotho, and the lesser known effects of excess phosphate (Pi), or phosphotoxicity. To examine the interplay between Pi, autophagy, and αKlotho, we used t...

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Podrobná bibliografie
Vydáno v:FASEB J
Hlavní autoři: Shi, Mingjun, Maique, Jenny, Shaffer, Joy, Davidson, Taylor, Sebti, Salwa, Fernández, Álvaro F., Zou, Zhongju, Yan, Shirley, Levine, Beth, Moe, Orson W., Hu, Ming Chang
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7286356/
https://ncbi.nlm.nih.gov/pubmed/31908069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201902127R
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