Bump-and-Hole Engineering Identifies Specific Substrates of Glycosyltransferases in Living Cells

Studying posttranslational modifications classically relies on experimental strategies that oversimplify the complex biosynthetic machineries of living cells. Protein glycosylation contributes to essential biological processes, but correlating glycan structure, underlying protein, and disease-releva...

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Bibliografske podrobnosti
izdano v:Mol Cell
Main Authors: Schumann, Benjamin, Malaker, Stacy Alyse, Wisnovsky, Simon Peter, Debets, Marjoke Froukje, Agbay, Anthony John, Fernandez, Daniel, Wagner, Lauren Jan Sarbo, Lin, Liang, Li, Zhen, Choi, Junwon, Fox, Douglas Michael, Peh, Jessie, Gray, Melissa Anne, Pedram, Kayvon, Kohler, Jennifer Jean, Mrksich, Milan, Bertozzi, Carolyn Ruth
Format: Artigo
Jezik:Inglês
Izdano: Cell Press 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7276986/
https://ncbi.nlm.nih.gov/pubmed/32325029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.03.030
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