Bump-and-Hole Engineering Identifies Specific Substrates of Glycosyltransferases in Living Cells

Studying posttranslational modifications classically relies on experimental strategies that oversimplify the complex biosynthetic machineries of living cells. Protein glycosylation contributes to essential biological processes, but correlating glycan structure, underlying protein, and disease-releva...

詳細記述

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書誌詳細
出版年:Mol Cell
主要な著者: Schumann, Benjamin, Malaker, Stacy Alyse, Wisnovsky, Simon Peter, Debets, Marjoke Froukje, Agbay, Anthony John, Fernandez, Daniel, Wagner, Lauren Jan Sarbo, Lin, Liang, Li, Zhen, Choi, Junwon, Fox, Douglas Michael, Peh, Jessie, Gray, Melissa Anne, Pedram, Kayvon, Kohler, Jennifer Jean, Mrksich, Milan, Bertozzi, Carolyn Ruth
フォーマット: Artigo
言語:Inglês
出版事項: Cell Press 2020
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7276986/
https://ncbi.nlm.nih.gov/pubmed/32325029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.03.030
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