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An enzymatic toolkit for selective proteolysis, detection, and visualization of mucin-domain glycoproteins
Densely O-glycosylated mucin domains are found in a broad range of cell surface and secreted proteins, where they play key physiological roles. In addition, alterations in mucin expression and glycosylation are common in a variety of human diseases, such as cancer, cystic fibrosis, and inflammatory...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7474620/ https://ncbi.nlm.nih.gov/pubmed/32817557 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2012196117 |
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