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An enzymatic toolkit for selective proteolysis, detection, and visualization of mucin-domain glycoproteins

Densely O-glycosylated mucin domains are found in a broad range of cell surface and secreted proteins, where they play key physiological roles. In addition, alterations in mucin expression and glycosylation are common in a variety of human diseases, such as cancer, cystic fibrosis, and inflammatory...

詳細記述

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Shon, D. Judy, Malaker, Stacy A., Pedram, Kayvon, Yang, Emily, Krishnan, Venkatesh, Dorigo, Oliver, Bertozzi, Carolyn R.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7474620/
https://ncbi.nlm.nih.gov/pubmed/32817557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2012196117
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