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Enzymatically active biomimetic micropropellers for the penetration of mucin gels

In the body, mucus provides an important defense mechanism by limiting the penetration of pathogens. It is therefore also a major obstacle for the efficient delivery of particle-based drug carriers. The acidic stomach lining in particular is difficult to overcome because mucin glycoproteins form vis...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Walker, Debora, Käsdorf, Benjamin T., Jeong, Hyeon-Ho, Lieleg, Oliver, Fischer, Peer
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4730841/
https://ncbi.nlm.nih.gov/pubmed/26824056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1500501
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