Systems Genetics in Human Endothelial Cells Identifies Non-coding Variants Modifying Enhancers, Expression, and Complex Disease Traits

The identification of causal variants and mechanisms underlying complex disease traits in humans is important for the progress of human disease genetics; this requires finding strategies to detect functional regulatory variants in disease-relevant cell types. To achieve this, we collected genetic an...

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Bibliographic Details
Published in:Am J Hum Genet
Main Authors: Stolze, Lindsey K., Conklin, Austin C., Whalen, Michael B., López Rodríguez, Maykel, Õunap, Kadri, Selvarajan, Ilakya, Toropainen, Anu, Örd, Tiit, Li, Jin, Eshghi, Anna, Solomon, Alice E., Fang, Yun, Kaikkonen, Minna U., Romanoski, Casey E.
Format: Artigo
Language:Inglês
Published: Elsevier 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7273528/
https://ncbi.nlm.nih.gov/pubmed/32442411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2020.04.008
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