Single-Cell Epigenomics and Functional Fine-Mapping of Atherosclerosis GWAS Loci

Genome-wide association studies have identified hundreds of loci associated with coronary artery disease (CAD). Many of these loci are enriched in cisregulatory elements but not linked to cardiometabolic risk factors nor to candidate causal genes, complicating their functional interpretation. OBJECT...

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Detalhes bibliográficos
Publicado no:Circ Res
Main Authors: Örd, Tiit, Õunap, Kadri, Stolze, Lindsey K., Aherrahrou, Redouane, Nurminen, Valtteri, Toropainen, Anu, Selvarajan, Ilakya, Lönnberg, Tapio, Aavik, Einari, Ylä-Herttuala, Seppo, Civelek, Mete, Romanoski, Casey E., Kaikkonen, Minna U.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2021
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8260472/
https://ncbi.nlm.nih.gov/pubmed/34024118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.121.318971
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