Meta-Analysis of Smooth Muscle Lineage Transcriptomes in Atherosclerosis and Their Relationships to In Vitro Models

BACKGROUND: Vascular smooth muscle cells (VSMC) exhibit phenotypic plasticity in atherosclerotic plaques, and among other approaches, has been modeled in vitro by cholesterol loading. METHODS: Meta-analysis of scRNA-seq data from VSMC lineage traced cells across five experiments of murine atheroscle...

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Bibliographic Details
Published in:Immunometabolism
Main Authors: Conklin, Austin C., Nishi, Hitoo, Schlamp, Florencia, Örd, Tiit, Õunap, Kadri, Kaikkonen, Minna U., Fisher, Edward A., Romanoski, Casey E.
Format: Artigo
Language:Inglês
Published: 2021
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8232871/
https://ncbi.nlm.nih.gov/pubmed/34178388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.20900/immunometab20210022
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