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Pharmacological or TRIB3-Mediated Suppression of ATF4 Transcriptional Activity Promotes Hepatoma Cell Resistance to Proteasome Inhibitor Bortezomib

SIMPLE SUMMARY: Proteasome inhibitors are currently used in the treatment of certain blood cancers, and clinical trials to treat solid tumors, including liver cancer, have also been conducted. However, different malignancies are not equally susceptible to proteasome inhibitors, and resistance to the...

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Bibliographic Details
Published in:Cancers (Basel)
Main Authors: Örd, Tiit, Örd, Daima, Kaikkonen, Minna U., Örd, Tõnis
Format: Artigo
Language:Inglês
Published: MDPI 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8150958/
https://ncbi.nlm.nih.gov/pubmed/34066165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13102341
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