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FGFR inhibition enhances sensitivity to radiation in non-small cell lung cancer.

Fibroblast growth factor receptors (FGFR) are commonly altered in non-small cell lung cancer (NSCLC). FGFRs activate multiple pathways including RAS/RAF/MAPK, PI3K/AKT and STAT, which may play a role in the cellular response to radiation. We investigated the effects of combining the selective FGFR 1...

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書誌詳細
出版年:Mol Cancer Ther
主要な著者: SenthilKumar, Gopika, Fisher, Michael M., Skiba, Justin H., Miller, Margot C., Brennan, Sean R., Kaushik, Saakshi, Bradley, Samantha T., Longhurst, Colin A., Buehler, Darya, Nickel, Kwangok P., Iyer, Gopal, Kimple, Randall J., Baschnagel, Andrew M.
フォーマット: Artigo
言語:Inglês
出版事項: 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7272291/
https://ncbi.nlm.nih.gov/pubmed/32371583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-19-0931
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