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Impact of immediate cryopreservation on the establishment of patient derived xenografts from head and neck cancer patients

BACKGROUND: Patient-derived xenografts established from human cancers are important tools for investigating novel anti-cancer therapies. Establishing PDXs requires a significant investment and many PDXs may be used infrequently due to their similarity to existing models, their growth rate, or the la...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Abel, Lindsey, Durmaz, Arda, Hu, Rong, Longhurst, Colin, Baschnagel, Andrew M., Wheeler, Deric, Scott, Jacob G., Kimple, Randall J.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8082827/
https://ncbi.nlm.nih.gov/pubmed/33910584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-021-02850-1
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