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Influence of Handling Conditions on the Establishment and Propagation of Head and Neck Cancer Patient Derived Xenografts

BACKGROUND: Patient derived xenografts (PDXs) for head and neck cancer (HNC) and other cancers represent powerful research platforms. Most groups implant patient tissue into immunodeficient mice immediately although the significance of this time interval is anecdotal. We tested the hypothesis that t...

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Autori principali: Stein, Andrew P., Saha, Sandeep, Liu, Cheng Z., Hartig, Gregory K., Lambert, Paul F., Kimple, Randall J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4072729/
https://ncbi.nlm.nih.gov/pubmed/24967635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100995
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