Fibroblast Growth Factor Receptors as Targets for Radiosensitization in Head and Neck Squamous Cell Carcinomas

PURPOSE: We examined the capacity of the pan-fibroblast growth factor receptor (FGFR) inhibitor AZD4547 to augment radiation response across a panel of head and neck squamous cell carcinoma (HNSCC) cell lines and xenografts. EXPERIMENTAL DESIGN: FGFR1, FGFR2, FGFR3 RNA in situ hybridization (ISH) ex...

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Detalhes bibliográficos
Publicado no:Int J Radiat Oncol Biol Phys
Main Authors: Fisher, Michael M., SenthilKumar, Gopika, Hu, Rong, Goldstein, Steve, Ong, Irene, Miller, Margot, Brennan, Sean R., Kaushik, Saakshi, Abel, Lindsey, Nickel, Kwangok P., Iyer, Gopal, Harari, Paul M., Kimple, Randall J., Baschnagel, Andrew M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7321889/
https://ncbi.nlm.nih.gov/pubmed/32298810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2020.03.040
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