Fibroblast Growth Factor Receptors as Targets for Radiosensitization in Head and Neck Squamous Cell Carcinomas

PURPOSE: We examined the capacity of the pan-fibroblast growth factor receptor (FGFR) inhibitor AZD4547 to augment radiation response across a panel of head and neck squamous cell carcinoma (HNSCC) cell lines and xenografts. EXPERIMENTAL DESIGN: FGFR1, FGFR2, FGFR3 RNA in situ hybridization (ISH) ex...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Int J Radiat Oncol Biol Phys
Prif Awduron: Fisher, Michael M., SenthilKumar, Gopika, Hu, Rong, Goldstein, Steve, Ong, Irene, Miller, Margot, Brennan, Sean R., Kaushik, Saakshi, Abel, Lindsey, Nickel, Kwangok P., Iyer, Gopal, Harari, Paul M., Kimple, Randall J., Baschnagel, Andrew M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7321889/
https://ncbi.nlm.nih.gov/pubmed/32298810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2020.03.040
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