Fibroblast Growth Factor Receptors as Targets for Radiosensitization in Head and Neck Squamous Cell Carcinomas

PURPOSE: We examined the capacity of the pan-fibroblast growth factor receptor (FGFR) inhibitor AZD4547 to augment radiation response across a panel of head and neck squamous cell carcinoma (HNSCC) cell lines and xenografts. EXPERIMENTAL DESIGN: FGFR1, FGFR2, FGFR3 RNA in situ hybridization (ISH) ex...

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Gepubliceerd in:Int J Radiat Oncol Biol Phys
Hoofdauteurs: Fisher, Michael M., SenthilKumar, Gopika, Hu, Rong, Goldstein, Steve, Ong, Irene, Miller, Margot, Brennan, Sean R., Kaushik, Saakshi, Abel, Lindsey, Nickel, Kwangok P., Iyer, Gopal, Harari, Paul M., Kimple, Randall J., Baschnagel, Andrew M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7321889/
https://ncbi.nlm.nih.gov/pubmed/32298810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2020.03.040
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