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Small RNA-mediated transgenerational silencing of histone genes impairs fertility in piRNA mutants
PIWI-interacting RNAs (piRNAs) promote fertility in many animals. Yet, whether this is due to their conserved role in repressing repetitive elements (REs) remains unclear. Here, we show that the progressive loss of fertility in Caenorhabditis elegans lacking piRNAs is not caused by derepression of R...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Nat Cell Biol |
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| Κύριοι συγγραφείς: | , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2020
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7272227/ https://ncbi.nlm.nih.gov/pubmed/32015436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-020-0462-7 |
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