Small RNA-mediated transgenerational silencing of histone genes impairs fertility in piRNA mutants

PIWI-interacting RNAs (piRNAs) promote fertility in many animals. Yet, whether this is due to their conserved role in repressing repetitive elements (REs) remains unclear. Here, we show that the progressive loss of fertility in Caenorhabditis elegans lacking piRNAs is not caused by derepression of R...

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Publicado en:Nat Cell Biol
Autores principales: Barucci, Giorgia, Cornes, Eric, Singh, Meetali, Li, Blaise, Ugolini, Martino, Samolygo, Aleksei, Didier, Celine, Dingli, Florent, Loew, Damarys, Quarato, Piergiuseppe, Cecere, Germano
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7272227/
https://ncbi.nlm.nih.gov/pubmed/32015436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-020-0462-7
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