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Sample-based modeling reveals bidirectional interplay between cell cycle progression and extrinsic apoptosis
Apoptotic cell death can be initiated through the extrinsic and intrinsic signaling pathways. While cell cycle progression promotes the responsiveness to intrinsic apoptosis induced by genotoxic stress or spindle poisons, this has not yet been studied conclusively for extrinsic apoptosis. Here, we c...
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| Veröffentlicht in: | PLoS Comput Biol |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7271993/ https://ncbi.nlm.nih.gov/pubmed/32497127 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007812 |
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