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Sample-based modeling reveals bidirectional interplay between cell cycle progression and extrinsic apoptosis

Apoptotic cell death can be initiated through the extrinsic and intrinsic signaling pathways. While cell cycle progression promotes the responsiveness to intrinsic apoptosis induced by genotoxic stress or spindle poisons, this has not yet been studied conclusively for extrinsic apoptosis. Here, we c...

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Bibliografiske detaljer
Udgivet i:PLoS Comput Biol
Main Authors: Imig, Dirke, Pollak, Nadine, Allgöwer, Frank, Rehm, Markus
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7271993/
https://ncbi.nlm.nih.gov/pubmed/32497127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007812
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