Sensitization of glioblastoma cells to TRAIL-induced apoptosis by IAP- and Bcl-2 antagonism

Due to the lack of effective treatments for glioblastoma (GBM), we here studied the responsiveness of GBM cell lines to the combination of death ligand, TRAIL and the IAP antagonist, TL32711 (Birinapant). Responses were highly heterogeneous, with synergistic apoptosis as well as treatment resistance...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Lincoln, Frank A., Imig, Dirke, Boccellato, Chiara, Juric, Viktorija, Noonan, Janis, Kontermann, Roland E., Allgöwer, Frank, Murphy, Brona M., Rehm, Markus
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6212537/
https://ncbi.nlm.nih.gov/pubmed/30385739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1160-2
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados