Predicting the cell death responsiveness and sensitization of glioma cells to TRAIL and temozolomide

Genotoxic chemotherapy with temozolomide (TMZ) is a mainstay of treatment for glioblastoma (GBM); however, at best, TMZ provides only modest survival benefit to a subset of patients. Recent insight into the heterogeneous nature of GBM suggests a more personalized approach to treatment may be necessa...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Weyhenmeyer, Birgit C., Noonan, Janis, Würstle, Maximilian L., Lincoln, Frank A., Johnston, Grainne, Rehm, Markus, Murphy, Brona M.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5308652/
https://ncbi.nlm.nih.gov/pubmed/27494880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10973
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