Bcl-2-mediated control of TRAIL-induced apoptotic response in the non-small lung cancer cell line NCI-H460 is effective at late caspase processing steps

Dysregulation of the mitochondrial signaling pathway of apoptosis induction represents a major hurdle in tumor therapy. The objective of the presented work was to investigate the role of the intrinsic (mitochondrial) apoptotic pathway in the non-small lung cancer cell line NCI-H460 upon induction of...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Danish, Lubna, Imig, Dirke, Allgöwer, Frank, Scheurich, Peter, Pollak, Nadine
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2018
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6013189/
https://ncbi.nlm.nih.gov/pubmed/29927992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0198203
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires