JZL184, A Monoacylglycerol Lipase Inhibitor, Induces Bone Loss in a Multiple Myeloma Model of Immunocompetent Mice

Multiple myeloma (MM) patients develop osteolysis characterised by excessive osteoclastic bone destruction and lack of osteoblast bone formation. Pharmacological manipulation of monoacylglycerol lipase (MAGL), an enzyme responsible for the degradation of the endocannabinoid 2-arachidonoyl glycerol (...

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Bibliografiske detaljer
Udgivet i:Calcif Tissue Int
Main Authors: Marino, Silvia, Carrasco, Giovana, Li, Boya, Shah, Karan M., Lath, Darren L., Sophocleous, Antonia, Lawson, Michelle A., Idris, Aymen I.
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2020
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7271071/
https://ncbi.nlm.nih.gov/pubmed/32285169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00223-020-00689-0
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