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Traceless native chemical ligation of lipid-modified peptide surfactants by mixed micelle formation
Biology utilizes multiple strategies, including sequestration in lipid vesicles, to raise the rate and specificity of chemical reactions through increases in effective molarity of reactants. We show that micelle-assisted reaction can facilitate native chemical ligations (NCLs) between a peptide-thio...
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| Veröffentlicht in: | Nat Commun |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7270136/ https://ncbi.nlm.nih.gov/pubmed/32493905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16595-w |
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